Episode 57 - Beyond the Physical: Why Treating Chronic Pain Requires Healing the Whole Person with Dr. Michelle Weiner

Episode 57 podcast cover featuring Dr. Michelle Weiner discussing holistic chronic pain treatment and healing the whole person

Dr. Michelle Weiner shares her evolution from interventional pain medicine to integrative ketamine-assisted therapy, emphasizing the biopsychosocial-spiritual model and treating central sensitization over traditional fibromyalgia approaches.

In this conversation, Dr. Michelle Weiner shares her evolution from chief resident in interventional pain medicine to pioneering integrative practitioner who treats chronic pain through a biopsychosocial-spiritual lens. Double board-certified in Interventional Pain Medicine, Physical Medicine, and Rehabilitation, Dr. Weiner reveals why traditional procedure-focused approaches often fail chronic pain patients and how she discovered more effective ways to create lasting healing.

Dr. Weiner's journey started with her background in nutritional science and athletics, leading her through physical medicine and rehabilitation before specializing in interventional pain. But day after day of performing procedures without truly connecting with patients left her frustrated and seeking deeper solutions. Her introduction to medical cannabis as chair of Florida's advisory committee opened her mind to personalized medicine and treating the whole person rather than just diagnosis codes.

You'll hear about her unique approach to fibromyalgia, which she reframes as "central sensitization" to empower rather than limit patients. Dr. Weiner explains how trauma and adverse childhood experiences prime the nervous system for hyperreactivity, leading to chronic pain that becomes centrally mediated rather than structurally based. Her practice now integrates cannabis protocols, ketamine therapy, and comprehensive team-based care to address the root causes of both physical and emotional pain.

Dr. Weiner also shares her personal ketamine experience during training, including a profound vision that later manifested in real life, demonstrating the spiritual dimension she now incorporates into treatment. You'll also hear practical insights about building an integrative practice, the importance of set and setting, and why true healing requires addressing the person with the diagnosis, not just the diagnosis itself.

What You'll Learn in This Episode:

  • · Career transition insights - How Dr. Weiner evolved from high-volume interventional procedures to relationship-based integrative medicine and why she felt traditional approaches were "stringing patients along"

  • Central sensitization framework - Why she avoids the term "fibromyalgia" and instead explains central sensitization to empower patients and create hope rather than diagnostic limitations

  • Biopsychosocial-spiritual model - How incorporating the spiritual dimension creates awe-like effects and connections that traditional medicine misses, supported by neuroscience research

  • Medical cannabis integration - Her role on Florida's Medical Cannabis Advisory Committee and how cannabis opened conversations about personalized medicine and treating individual endocannabinoid systems

  • Trauma's role in chronic pain - How adverse childhood experiences and physical trauma prime the nervous system for hyperreactivity and chronic pain development

  • Practice building strategies - Practical advice about insurance credentialing, marketing to other providers, creating therapeutic environments, and building multidisciplinary teams

  • Set and setting importance - Why the physical environment, staff training, and patient preparation are crucial for maximizing ketamine therapy outcomes

  • Patient education approaches - How she explains that healing happens during the neuroplastic window after ketamine, not during the infusion itself, and why "more is not better"

  • Team-based care model - Working with coaches, therapists, and specialists trained in pain reprocessing therapy and somatic approaches to support comprehensive healing

Key Takeaways:

  • Traditional chronic pain treatment often perpetuates suffering - Repeatedly treating MRI findings with procedures and medications without addressing the whole person can actually worsen chronification and create hopelessness in patients

  • Language and framing matter profoundly - Using "central sensitization" instead of "fibromyalgia" empowers patients to understand their condition as changeable rather than a fixed diagnosis, opening possibilities for healing

  • The biopsychosocial-spiritual model is scientifically supported - Incorporating spiritual dimensions isn't "woo-woo" but backed by neuroscience research on awe, connection, and the brain's response to transcendent experiences

  • Chronic pain can stem from nervous system hyperreactivity - Trauma and adverse experiences create hypervigilant states where the nervous system perceives threats everywhere, requiring safety and nervous system regulation approaches

  • Ketamine works as a catalyst, not a cure - The real therapeutic value occurs during the neuroplastic window after treatment when patients can make psychological and behavioral changes with proper integration support

  • Authentic relationships drive healing - Moving from procedure-focused to relationship-based medicine allows providers to understand the psychosocial aspects of pain and create genuine connections with patients

  • Lower ketamine doses can be more effective - For patients seeking healing rather than just pain relief, lower doses that allow insight and body awareness often produce better long-term outcomes than higher sedating doses

  • Integration is essential for lasting change - Without proper preparation and post-treatment integration work, ketamine becomes just another medication rather than a transformative healing tool

  • Multidisciplinary teams enhance outcomes - Working with coaches, therapists, and specialists allows providers to address different aspects of healing while leveraging complementary skills and perspectives

Listen to the episode on Apple Podcasts, Spotify, Overcast, or on your favorite podcast platform. Watch the discussion on YouTube here.

KSP EP57 - Beyond the Physical with Dr. Michelle Weiner
Ketamine StartUp

Episode 57 show notes:

  • 00:00:00 - Teaser: Heart-Forward Medicine and True Passion 

  • 00:00:19 - Introduction and Dr. Weiner's Background Overview

  • 00:02:00 - Educational Journey: From Nutrition Science to Pain Medicine 

  • 00:05:13 - Colleague Reactions to Non-Traditional Approach

  • 00:08:37 - The Pivotal Moment: From Procedures to Purpose 

  • 00:11:04 - Cannabis Integration and Personalized Medicine Discovery 

  • 00:13:43 - Biopsychosocial Model and Pain Neuroscience Education 

  • 00:17:09 - Trauma Patterns and Chronic Pain Development 

  • 00:19:54 - Reframing Fibromyalgia as Central Sensitization 

  • 00:23:54 - Adding the Spiritual Dimension: Biopsychosocial-Spiritual Model 

  • 00:29:07 - Personal Ketamine Experience and Training Story 

  • 00:34:22 - Practice Building: From Employee to Business Owner 

  • 00:38:18 - Set and Setting: Creating Therapeutic Environments 

  • 00:41:48 - Patient Misconceptions and Education Strategies

  • 00:47:08 - Rapid Fire Questions: 

  • 00:53:55 - Advice to 18-Year-Old Self

  • 00:55:34 - Final Thoughts: Pain Complexity and Nervous System Healing 

  • 00:56:32 - Contact Information and Practice Locations 

  • 00:57:29 - Ending and Show Resources

Thanks for Listening



Professional Education Disclaimer: This content is intended exclusively for licensed healthcare professionals and should not be used by patients for self-treatment or self-education. The information presented reflects individual provider experiences and should not replace clinical judgment, professional training, or comprehensive research. Healthcare providers must conduct their own due diligence, consult current literature, and evaluate treatment approaches within their specific practice context and regulatory environment. This educational content does not constitute medical advice for specific patients or clinical situations - treatment decisions should always be based on individual patient assessment and adherence to professional medical standards.

Frequently Asked Questions

What made Dr. Weiner transition away from traditional interventional pain medicine? 

Dr. Weiner described feeling frustrated with the repetitive nature of procedures without really connecting with patients. She explained: "Day after day of going into a procedure room and seeing someone lie down face down and just getting ready to do an epidural injection without really communicating with the patient and seeing their face, I felt like I lost a lot of my ability to properly treat that person." She felt like traditional approaches were "stringing these patients along" rather than addressing the root causes of chronic pain.

Why does Dr. Weiner avoid using the term "fibromyalgia"? 

According to Dr. Weiner, she calls it "central sensitization" instead because "I feel like even giving someone the diagnosis of fibromyalgia keeps them stuck." She explained that when patients get that diagnosis, "they're gonna go online and look up what that is, then they're gonna try to figure out what's the best medication or treatment for them." Since there aren't good FDA-approved options for fibromyalgia, this creates hopelessness. Using "central sensitization" instead allows her to explain the neuroplastic changes and empower patients.

What is Dr. Weiner's "biopsychosocial-spiritual" model? 

Dr. Weiner adds the spiritual component to the traditional biopsychosocial model, explaining that "the spiritual component can create this awe-like effect and something like awe where it's something that you've never experienced before, it's new to the brain." She believes this helps people realize "other things are possible" and connects them to something bigger than themselves. She referenced "The Awakened Brain" by Lisa Miller as providing the science behind spirituality.

How does Dr. Weiner approach ketamine dosing differently? 

Dr. Weiner emphasizes that "more is not better" and that "a lot of the insight can actually be from lower doses, where they're able to quiet their mind, get into their body a little bit more." She explained that when patients are too sedated or in an altered state for too long, "there's a lack of insight when you are too sedated or when you're in a state for too long that you can't remember."

What role does trauma play in chronic pain according to Dr. Weiner?

Dr. Weiner explained that taking a good history to understand "when the injury or trauma started that primed the nervous system for this hyperreactivity" is crucial. She noted that "there's usually something that can tie into it when that started," whether it's physical trauma like a car accident or "adverse childhood events [that] led them to this hypersensitivity within their nervous system, and now they're in this hypervigilant state looking at the world like it's a dangerous place to be."

How important is the integration component of ketamine therapy? 

Dr. Weiner stressed that "the few days or weeks after [ketamine] are very significant to how your nervous system can shift over time." She explained that without integration, "it's sort of like giving someone the diagnosis of fibromyalgia and saying, 'You are now in this box'... as opposed to, 'Go home and start to open to new ways of thinking about yourself or changing some of your beliefs.'" She emphasized that if patients don't do the integration work, they might conclude "the ketamine didn't work" when the real issue is lack of follow-through.

What practical advice does Dr. Weiner give for starting an integrative pain practice? 

Dr. Weiner highlighted several key elements: getting on as many insurance panels as possible, focusing on the physical space and creating quiet, safe environments with recliners and music, marketing to other providers like therapists and psychiatrists rather than competing with them, and hiring people who understand the importance of setting. She emphasized that "the teamwork is really very important to a successful practice" and working with coaches and therapists who complement your skills.


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Episode 56 - Breaking: Four Major Developments Reshaping Ketamine and Psychedelic Therapy