Welcome to the Ketamine Startup Podcast!
The FIRST podcast about ketamine therapy for those in the industry.
HI! We’re Sam and Kim Ko, two physicians who have ventured into universe of ketamine therapy and medical entrepreneurship. We’ve learned a lot of lessons, taught several clinicians like yourself, and made a few friends along the way.
We want to share our experience and knowledge, plus that of the industry pioneers and leaders through our interviews.
If you’re ready to boldly go where a few medical professionals have gone before, download and listen to our podcast today. 🚀
Episode 55 - Career Reinvention Success: Why Going Backwards Made Dr. Ruchir Gupta Advance
Dr. Ruchir Gupta shares his unconventional journey from established anesthesiologist back to pain fellowship training, then building a successful multi-location practice. Learn why he believes physicians create artificial mental barriers around entrepreneurship, his specialized fibromyalgia protocols achieving 80% success rates, and practical insights about monitoring standards and business development for medical professionals considering practice ownership.
Episode 54 -The Public Perception Reality Check: Psychedelic Culture and Ketamine Therapy with Shane Mauss
Comedian Shane Mauss shares cultural insider perspectives from years of psychedelic comedy tours, revealing how public perception has evolved since 2004 and what this means for ketamine providers today. Learn why scientific rigor trumps wellness industry hype and how to educate patients navigating complex cultural messages about psychedelic therapy.
Episode 53 - The Collective Lie in Ketamine Therapy (Part 2): MSKIT Protocol and the Future of Ketamine Therapy
In Part 2, Charles Miller details his evidence-based MSKIT protocol for optimal ketamine therapy outcomes, explains when therapeutic integration should actually occur, and shares his vision for advancing the field through rigorous science rather than experiential speculation.
Episode 52 -The Collective Lie in Ketamine Therapy (Part 1): Why the Experience Isn't the Treatment
In this episode Charles Miller challenges ketamine therapy's focus on psychedelic experiences, arguing that neuroplasticity science shows we're emphasizing the wrong mechanisms and reducing treatment success rates.
Episode 51 - The 4 Ketamine Clinic Business Stages: How to Know Where You Are and What to Do Next
Learn the 4 predictable life cycle stages every ketamine clinic experiences, from startup survival to strategic growth. Discover how to identify your current phase, understand normal challenges, and make value-based decisions that align with your practice goals rather than reactive choices
Episode 50 - Beyond Cookie-Cutter Protocols: Inna Zelikman's Comprehensive Approach to Ketamine and Psilocybin Therapy
MAPS-certified psychiatric nurse practitioner Inna Zelikman shares how her personal psychedelic healing journey transformed her approach to individualized ketamine and psilocybin patient care.
Episode 49 - Texas Medical Board Proposes Comprehensive Ketamine Therapy Regulations - What It Means for the Industry
Texas Medical Board proposes comprehensive ketamine clinic regulations including mandatory registration, onsite physician requirements, and enhanced monitoring standards that could reshape the entire industry.
Episode 48 - Does a Physician Need to Be Present During Ketamine Infusions?
Discover the real answer to physician presence requirements during ketamine infusions. Learn about the current regulatory landscape, scope of practice issues for different healthcare providers, various staffing models clinics use, and balancing risk management with patient care.
Episode 47 - What You Should Tell Your Ketamine Patients: 4 Things To Expect During Their Infusion (Episodes from the Vault)
From our vault: The patient communication masterclass originally from our Ketamine Startup 101 mastermind session. This essential episode covers four critical patient preparation strategies, team training protocols, and emotional safety frameworks.
Episode 46 - The Clinician's Guide to Ketamine Therapy (Episodes from the Vault)
From our vault: Sam's complete clinical overview originally presented to UCLA and Betty Ford Fellowship. This foundational episode covers ketamine's 50-year history, NMDA receptor mechanism, patient selection criteria, dosing protocols, and safety considerations.
Episode 45 - From Emergency Medicine to Psychospiritual Healing: Dr. Randy Frederick's Ketamine Clinic Journey
Dr. Randy Frederick, former military flight surgeon and ER physician, discusses his transformation from traditional clinical ketamine protocols to psychospiritual healing approaches. Learn why he views ketamine as a catalyst rather than cure, his insights on consciousness work, business ownership challenges, and the future of psychedelic medicine
Episode 44- Building a Trauma-Informed Ketamine Practice with Dr. Jack Hay & Dr. Harry Pepper
ER physician Dr. Jack Hay and psychologist Dr. Harry Pepper share their unique partnership approach to ketamine therapy at Oberlin Ketamine Clinic. Topics include patient-chosen music playlists, trauma-informed care principles, integration coaching versus traditional therapy, practicing from values, and lessons from their first year opening a clinic in Ohio.
Episode 43- What Licenses Do You Need to Open a Ketamine Clinic?
Learn which licenses you need to legally open a ketamine infusion clinic. This episode covers essential medical licenses like DEA and NPI, unfamiliar business permits including FNP and DBA, and why requirements vary significantly by state and county.
Episode 42 - Essential Risk Management: DEA Compliance & Insurance for Ketamine Clinics
Retired DEA agent reveals audit triggers while an insurance expert shares costly coverage mistakes. Essential compliance and protection strategies every ketamine clinic owner needs to know.
Episode 41 - Pioneers Who Challenged Medical Orthodoxy: Howard Kornfeld, Joe Tafur & Mel Herbert
Learn from three medical pioneers who refused to accept "no" as an answer. Dr. Howard Kornfeld revolutionized addiction treatment, Dr. Joe Tafur bridges traditional and modern healing, and Dr. Mel Herbert transformed global medical education. Their stories prove individual practitioners can create lasting systemic change.
Episode 40 - Scaling Ketamine Clinics: From Pilot to Five Locations with Dr. Nico Grundmann
Emergency physician Dr. Nico Grundmann shares his journey from ER doctor to CEO, scaling Ember Health from one pilot location to five ketamine clinics across New York City.
Episode 39 - Pain, Addiction, and Medical Practice with Dr. Howard Kornfeld
Dr. Howard Kornfeld shares five decades of medical insights, from emergency medicine and nuclear activism to pioneering buprenorphine treatment and building Recovery Without Walls clinic.
Episode 38 - Our Ketamine Clinic Origin Story: From Hospital Employment to Independence
Kim and Sam Ko share their complete journey from hospital-employed physicians to successful ketamine clinic owners. Learn how they discovered ketamine research, managed the risks of leaving traditional employment, overcame social resistance, and built Reset Ketamine from four treatments in month one to a thriving practice.
Episode 37 - Mindset Mnemonics for Ketamine Clinic Success
Learn four essential mindset tools that separate successful ketamine clinics from those that struggle. Kim and Sam teach simple mnemonics for staying focused during chaos, prioritizing effectively, maintaining presence, and controlling negative thoughts that can derail your practice
Episode 36 - Building Healing Communities with Mike Margolies
Discover why individual ketamine therapy isn't enough and shares practical strategies for building healing communities that address systemic mental health challenges with Mike Margolies, co-founder of Global Psychedelic Society.